Impact of Cigarette Smoking on Serum C-Reactive Protein Level among Sudanese Patients with Chronic Periodontitis at Khartoum Teaching Dental Hospital
Ahmed, Leina, A.M – Clinical MD, Ramadan, AbdelRahman, M.- PhD

Background: The C-reactive protein is a non-specific inflammatory acute-phase plasma protein whose levels rise in response to inflammation. An association has been demonstrated between chronic periodontal disease and an elevated level of C-reactive protein. Smoking is an established risk factor for periodontal disease. Therefore, the combination of chronic periodontit is and smoking may be a high risk for individual health. Methods: An observational analytical cross-sectional hospital-based study was conducted on 84 participants (49 men and 35 women) categorised into four groups; Group A: included systematically healthy non-smokers without chronic periodontitis. Group B: included systematically healthy non-smokers with chronic periodontitis. Group C: included systematically healthy smokers without chronic periodontitis, while Group D: included systematically healthy smokers with chronic periodontitis. Results: The independent sample t-test demonstrated no statistically significant differences inthe serum levels of CRP between groups (A & B), (C & D), (A & C), (B & D) using a significant level (0.05). Conclusions: The present study concluded that (I) periodontal disease does not significantly affect the serum levels of C reactive protein (II) smoking does not contribute to an elevated level of C reactive protein (III) smoking has no impact on serum level of C reactive protein on periodontitis patients.

Full Text: PDF     DOI: 10.15640/ijhs.v9n1a11